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Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage
Frizzled receptors are the mediators of the wnt canonical and non-canonical pathways, which play fundamental roles in cell differentiation and organism development. A large body of work indicates that dysregulation of wnt signalling is a feature of oncogenic transformation, but most of the studies p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541719/ https://www.ncbi.nlm.nih.gov/pubmed/28737757 http://dx.doi.org/10.1038/oncsis.2017.69 |