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ASCT2 regulates glutamine uptake and cell growth in endometrial carcinoma

Glutamine commonly becomes a conditionally essential amino acid in cancer. Glutamine is supplied to the cell by transporters such as ASCT2 (SLC1A5), which is frequently upregulated in multiple cancers. Here we investigated the expression of ASCT2 in endometrial carcinoma, and evaluated the contribut...

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Detalles Bibliográficos
Autores principales: Marshall, A D, van Geldermalsen, M, Otte, N J, Lum, T, Vellozzi, M, Thoeng, A, Pang, A, Nagarajah, R, Zhang, B, Wang, Q, Anderson, L, Rasko, J E J, Holst, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541720/
https://www.ncbi.nlm.nih.gov/pubmed/28759021
http://dx.doi.org/10.1038/oncsis.2017.70