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Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial

BACKGROUND: Few clinical trials have investigated the safety and efficacy of mesenchymal stem cells for the management of post-traumatic osteoarthritis. The objectives of this pilot study were to determine the safety and tolerability and to explore the efficacy of a single intra-articular injection...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Shimmin, Andrew, Ghosh, Peter, Marks, Paul, Linklater, James, Connell, David, Hall, Stephen, Skerrett, Donna, Itescu, Silviu, Cicuttini, Flavia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541727/
https://www.ncbi.nlm.nih.gov/pubmed/28768528
http://dx.doi.org/10.1186/s13075-017-1391-0