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Live-cell calcium imaging of adherent and non-adherent GL261 cells reveals phenotype-dependent differences in drug responses

BACKGROUND: The tumor-derived GL261 cell line is used as a model for studying glioblastoma and other high-grade gliomas, and can be cultured adherently or as free-floating aggregates known as neurospheres. These different culture conditions give rise to distinct phenotypes, with increased tumorigeni...

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Detalles Bibliográficos
Autores principales: Strong, Averey D., Daniels, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541742/
https://www.ncbi.nlm.nih.gov/pubmed/28768483
http://dx.doi.org/10.1186/s12885-017-3507-y