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A Case of Fulminant Meningococcemia: It Is All in the Complement

Eculizumab is a novel monoclonal antibody that inhibits complement-mediated hemolysis in patients with paroxysmal nocturnal hemoglobinuria (PNH). Complement deficiency is a well-known risk factor for meningococcal infection. We describe a case of a young patient with PNH treated with eculizumab who...

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Detalles Bibliográficos
Autores principales: Hawkins, Kellie L., Hoffman, Mariah, Okuyama, Sonia, Rowan, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541820/
https://www.ncbi.nlm.nih.gov/pubmed/28808592
http://dx.doi.org/10.1155/2017/6093695