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Binding of ZO-1 to α5β1 integrins regulates the mechanical properties of α5β1–fibronectin links

Fundamental processes in cell adhesion, motility, and rigidity adaptation are regulated by integrin-mediated adhesion to the extracellular matrix (ECM). The link between the ECM component fibronectin (fn) and integrin α5β1 forms a complex with ZO-1 in cells at the edge of migrating monolayers, regul...

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Detalles Bibliográficos
Autores principales: González-Tarragó, Víctor, Elosegui-Artola, Alberto, Bazellières, Elsa, Oria, Roger, Pérez-González, Carlos, Roca-Cusachs, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541835/
https://www.ncbi.nlm.nih.gov/pubmed/28251923
http://dx.doi.org/10.1091/mbc.E17-01-0006