Mechanical regulation of cardiac fibroblast profibrotic phenotypes

Cardiac fibrosis is a serious condition currently lacking effective treatments. It occurs as a result of cardiac fibroblast (CFB) activation and differentiation into myofibroblasts, characterized by proliferation, extracellular matrix (ECM) production and stiffening, and contraction due to the expre...

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Detalles Bibliográficos
Autores principales: Herum, Kate M., Choppe, Jonas, Kumar, Aditya, Engler, Adam J., McCulloch, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541838/
https://www.ncbi.nlm.nih.gov/pubmed/28468977
http://dx.doi.org/10.1091/mbc.E17-01-0014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541838/
https://www.ncbi.nlm.nih.gov/pubmed/28468977
http://dx.doi.org/10.1091/mbc.E17-01-0014

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