Effects of substrate stiffness and actomyosin contractility on coupling between force transmission and vinculin–paxillin recruitment at single focal adhesions

Focal adhesions (FAs) regulate force transfer between the cytoskeleton and ECM–integrin complexes. We previously showed that vinculin regulates force transmission at FAs. Vinculin residence time in FAs correlated with applied force, supporting a mechanosensitive model in which forces stabilize vincu...

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Detalles Bibliográficos
Autores principales: Zhou, Dennis W., Lee, Ted T., Weng, Shinuo, Fu, Jianping, García, Andrés J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541841/
https://www.ncbi.nlm.nih.gov/pubmed/28468976
http://dx.doi.org/10.1091/mbc.E17-02-0116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541841/
https://www.ncbi.nlm.nih.gov/pubmed/28468976
http://dx.doi.org/10.1091/mbc.E17-02-0116

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