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Rear-polarized Wnt5a-receptor-actin-myosin-polarity (WRAMP) structures promote the speed and persistence of directional cell migration

In contrast to events at the cell leading edge, rear-polarized mechanisms that control directional cell migration are poorly defined. Previous work described a new intracellular complex, the Wnt5a-receptor-actomyosin polarity (WRAMP) structure, which coordinates the polarized localization of MCAM, a...

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Detalles Bibliográficos
Autores principales: Connacher, Mary Katherine, Tay, Jian Wei, Ahn, Natalie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541843/
https://www.ncbi.nlm.nih.gov/pubmed/28592632
http://dx.doi.org/10.1091/mbc.E16-12-0875