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Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

The cell nucleus must continually resist and respond to intercellular and intracellular mechanical forces to transduce mechanical signals and maintain proper genome organization and expression. Altered nuclear mechanics is associated with many human diseases, including heart disease, progeria, and c...

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Detalles Bibliográficos
Autores principales: Stephens, Andrew D., Banigan, Edward J., Adam, Stephen A., Goldman, Robert D., Marko, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541848/
https://www.ncbi.nlm.nih.gov/pubmed/28057760
http://dx.doi.org/10.1091/mbc.E16-09-0653