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Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus
The cell nucleus must continually resist and respond to intercellular and intracellular mechanical forces to transduce mechanical signals and maintain proper genome organization and expression. Altered nuclear mechanics is associated with many human diseases, including heart disease, progeria, and c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541848/ https://www.ncbi.nlm.nih.gov/pubmed/28057760 http://dx.doi.org/10.1091/mbc.E16-09-0653 |