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Orientation and repositioning of chromosomes correlate with cell geometry–dependent gene expression
Extracellular matrix signals from the microenvironment regulate gene expression patterns and cell behavior. Using a combination of experiments and geometric models, we demonstrate correlations between cell geometry, three-dimensional (3D) organization of chromosome territories, and gene expression....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541849/ https://www.ncbi.nlm.nih.gov/pubmed/28615317 http://dx.doi.org/10.1091/mbc.E16-12-0825 |