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Orientation and repositioning of chromosomes correlate with cell geometry–dependent gene expression

Extracellular matrix signals from the microenvironment regulate gene expression patterns and cell behavior. Using a combination of experiments and geometric models, we demonstrate correlations between cell geometry, three-dimensional (3D) organization of chromosome territories, and gene expression....

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Detalles Bibliográficos
Autores principales: Wang, Yejun, Nagarajan, Mallika, Uhler, Caroline, Shivashankar, G. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541849/
https://www.ncbi.nlm.nih.gov/pubmed/28615317
http://dx.doi.org/10.1091/mbc.E16-12-0825