Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation

Synergistic cues from extracellular matrix and soluble factors are often obscure in differentiation. Here the rigidity of cross-linked collagen synergizes with retinoids in the osteogenesis of human marrow mesenchymal stem cells (MSCs). Collagen nanofilms serve as a model matrix that MSCs can easily...

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Detalles Bibliográficos
Autores principales: Ivanovska, Irena L., Swift, Joe, Spinler, Kyle, Dingal, Dave, Cho, Sangkyun, Discher, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541850/
https://www.ncbi.nlm.nih.gov/pubmed/28566555
http://dx.doi.org/10.1091/mbc.E17-01-0010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541850/
https://www.ncbi.nlm.nih.gov/pubmed/28566555
http://dx.doi.org/10.1091/mbc.E17-01-0010

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