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Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation
Synergistic cues from extracellular matrix and soluble factors are often obscure in differentiation. Here the rigidity of cross-linked collagen synergizes with retinoids in the osteogenesis of human marrow mesenchymal stem cells (MSCs). Collagen nanofilms serve as a model matrix that MSCs can easily...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541850/ https://www.ncbi.nlm.nih.gov/pubmed/28566555 http://dx.doi.org/10.1091/mbc.E17-01-0010 |