Examining a role for PKG Iα oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity

BACKGROUND: Protein kinase G (PKG) Iα is the end-effector kinase that mediates nitric oxide (NO)-dependent and oxidant-dependent vasorelaxation to maintain blood pressure during health. A hallmark of cardiovascular disease is attenuated NO production, which in part is caused by NO Synthase (NOS) unc...

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Detalles Bibliográficos
Autores principales: Rudyk, Olena, Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541991/
https://www.ncbi.nlm.nih.gov/pubmed/28690194
http://dx.doi.org/10.1016/j.freeradbiomed.2017.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541991/
https://www.ncbi.nlm.nih.gov/pubmed/28690194
http://dx.doi.org/10.1016/j.freeradbiomed.2017.07.007

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