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Down Syndrome-Associated Diabetes Is Not Due To a Congenital Deficiency in β Cells

AIMS/HYPOTHESIS: We sought to establish whether the increased incidence of diabetes associated with Down syndrome was due to a congenital deficit in β cells. METHODS: The pancreas was obtained at autopsy from nondiabetic subjects with Down syndrome (n = 29) and age-matched nondiabetic control subjec...

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Detalles Bibliográficos
Autores principales: Butler, Alexandra E., Sacks, Wendy, Rizza, Robert A., Butler, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542008/
https://www.ncbi.nlm.nih.gov/pubmed/28782055
http://dx.doi.org/10.1210/js.2016-1042