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Egr-1 and RNA POL II facilitate glioma cell GDNF transcription induced by histone hyperacetylation in promoter II

The specific mechanisms for epigenetic regulation of gene transcription remain to be elucidated. We previously demonstrated that hyperacetylation of histone H3K9 in promoter II of glioma cells promotes high transcription of the glial cell line-derived neurotrophic factor (GDNF) gene. This hyperacety...

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Detalles Bibliográficos
Autores principales: Zhang, Bao-Le, Guo, Ting-Wen, Gao, Le-Le, Ji, Guang-Quan, Gu, Xiao-He, Shao, Yu-Qi, Yao, Rui-Qin, Gao, Dian-Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542170/
https://www.ncbi.nlm.nih.gov/pubmed/28187447
http://dx.doi.org/10.18632/oncotarget.15126