Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex

MicroRNAs have been proved to participate in multiple biological processes in cancers. For developing resistance to cytotoxic drug, cancer cells, especially the cancer stem cells, usually change their microRNA expression profile to survive in hostile environments. In the present study, we found that...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Rui, Xu, Jian, Zhao, Jian, Bai, Jinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542179/
https://www.ncbi.nlm.nih.gov/pubmed/28423356
http://dx.doi.org/10.18632/oncotarget.16779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542179/
https://www.ncbi.nlm.nih.gov/pubmed/28423356
http://dx.doi.org/10.18632/oncotarget.16779

Ejemplares similares