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PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line

BACKGROUND: Neuroendocrine cervical carcinoma (NECC) is a rare and aggressive subtype of cervical cancer. To date, no NECC cell-based model is available, which hinders the development of new therapeutic strategies for NECC. In this study, we derived a new NECC cell line from an ex vivo biopsy and us...

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Detalles Bibliográficos
Autores principales: Lai, Zih-Yin, Yeo, Hsin-Yueh, Chen, Ya-Tse, Chang, Kuo-Ming, Chen, Tze-Chien, Chuang, Yung-Jen, Chang, Shing-Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542189/
https://www.ncbi.nlm.nih.gov/pubmed/28484083
http://dx.doi.org/10.18632/oncotarget.17335