Molecular characterization of circulating tumor cells from patients with metastatic breast cancer reflects evolutionary changes in gene expression under the pressure of systemic therapy

Resistance to systemic therapy is a major problem in metastatic breast cancer (MBC) that can be explained by initial tumor heterogeneity as well as by evolutionary changes during therapy and tumor progression. Circulating tumor cells (CTCs) detected in a liquid biopsy can be sampled and characterize...

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Detalles Bibliográficos
Autores principales: Aaltonen, Kristina E., Novosadová, Vendula, Bendahl, Pär-Ola, Graffman, Cecilia, Larsson, Anna-Maria, Rydén, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542207/
https://www.ncbi.nlm.nih.gov/pubmed/28489591
http://dx.doi.org/10.18632/oncotarget.17271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542207/
https://www.ncbi.nlm.nih.gov/pubmed/28489591
http://dx.doi.org/10.18632/oncotarget.17271

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