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12-O-tetradecanoylphorbol-13-acetate (TPA) increases murine intestinal crypt stem cell survival following radiation injury

Radiation enteropathy is a common complication in cancer patients following radiation therapy. Thus, there is a need for agents that can protect the intestinal epithelium against radiation. 12-O-tetradecanoylphorbol-13-acetate (TPA) has been shown to induce differentiation and/or apoptosis in multip...

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Detalles Bibliográficos
Autores principales: Liang, Yaojie, Zhou, Hongwei, Yao, Yibing, Deng, Ailing, Wang, Zhihong, Gao, Boning, Zhou, Minhang, Cui, Yu, Wang, Lili, Zhou, Lei, Wang, Bianhong, Wang, Li, Liu, Anqi, Qiu, Lanlan, Qian, Kun, Lu, Yejian, Deng, Wanping, Zheng, Xi, Han, Zhengtao, Li, Yonghui, Sun, Junzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542208/
https://www.ncbi.nlm.nih.gov/pubmed/28545017
http://dx.doi.org/10.18632/oncotarget.17269