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Enhanced antitumor efficacy of cisplatin for treating ovarian cancer in vitro and in vivo via transferrin binding

Cisplatin is a widely used anticancer drug, while non-targeted delivery, development of drug resistance, and serious side effects significantly limit its clinical use. In order to improve the tumor-targeting properties of cisplatin, transferrin (Tf) was employed as a carrier to transfer cisplatin in...

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Detalles Bibliográficos
Autores principales: Peng, Huifang, Jin, Hongwei, Zhuo, Huiqin, Huang, Heqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542211/
https://www.ncbi.nlm.nih.gov/pubmed/28484093
http://dx.doi.org/10.18632/oncotarget.17316