ARID1B alterations identify aggressive tumors in neuroblastoma

Targeted panel sequencing was performed to determine molecular targets and biomarkers in 72 children with neuroblastoma. Frequent genetic alterations were detected in ALK (16.7%), BRCA1 (13.9%), ATM (12.5%), and PTCH1 (11.1%) in an 83-gene panel. Molecular targets for targeted therapy were identifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Soo Hyun, Kim, Jung-Sun, Zheng, Siyuan, Huse, Jason T., Bae, Joon Seol, Lee, Ji Won, Yoo, Keon Hee, Koo, Hong Hoe, Kyung, Sungkyu, Park, Woong-Yang, Sung, Ki W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542239/
https://www.ncbi.nlm.nih.gov/pubmed/28521285
http://dx.doi.org/10.18632/oncotarget.17500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542239/
https://www.ncbi.nlm.nih.gov/pubmed/28521285
http://dx.doi.org/10.18632/oncotarget.17500

Ejemplares similares