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Dihydroartemisinin induces autophagy-dependent death in human tongue squamous cell carcinoma cells through DNA double-strand break-mediated oxidative stress

Dihydroartemisinin is an effective antimalarial agent with multiple biological activities. In the present investigation, we elucidated its therapeutic potential and working mechanism on human tongue squamous cell carcinoma (TSCC). It was demonstrated that dihydroartemisinin could significantly inhib...

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Detalles Bibliográficos
Autores principales: Shi, Xinli, Wang, Li, Li, Xiaoming, Bai, Jing, Li, Jianchun, Li, Shenghao, Wang, Zeming, Zhou, Mingrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542242/
https://www.ncbi.nlm.nih.gov/pubmed/28526807
http://dx.doi.org/10.18632/oncotarget.17520