CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy

Though CNOT2 is involved in regulation of adipogenic differentiation, apoptotic cell death and metastasis, the underlying autophagic mechanism of CNOT2 was unknown until now. Thus, in the present study, the critical role of CNOT2 in autophagy was elucidated in association with p62/SQSTM1 signaling....

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Detalles Bibliográficos
Autores principales: Jeong, Kwon, Kwon, Hee Young, Jeong, Myoung Seok, Sohn, Eun Jung, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542246/
https://www.ncbi.nlm.nih.gov/pubmed/28537904
http://dx.doi.org/10.18632/oncotarget.17682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542246/
https://www.ncbi.nlm.nih.gov/pubmed/28537904
http://dx.doi.org/10.18632/oncotarget.17682

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