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CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy
Though CNOT2 is involved in regulation of adipogenic differentiation, apoptotic cell death and metastasis, the underlying autophagic mechanism of CNOT2 was unknown until now. Thus, in the present study, the critical role of CNOT2 in autophagy was elucidated in association with p62/SQSTM1 signaling....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542246/ https://www.ncbi.nlm.nih.gov/pubmed/28537904 http://dx.doi.org/10.18632/oncotarget.17682 |