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5azadC treatment upregulates miR-375 level and represses HPV16 E6 expression

High-risk human papillomaviruses are the etiological agents of cervical cancer and HPV16 is the most oncogenic genotype. Immortalization and transformation of infected cells requires the overexpression of the two viral oncoproteins E6 and E7 following HPV DNA integration into the host cell genome. I...

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Detalles Bibliográficos
Autores principales: Morel, Adrien, Baguet, Aurélie, Perrard, Jérôme, Demeret, Caroline, Jacquin, Elise, Guenat, David, Mougin, Christiane, Prétet, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542257/
https://www.ncbi.nlm.nih.gov/pubmed/28521287
http://dx.doi.org/10.18632/oncotarget.17575