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Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging

Hepatic steatosis is frequently observed in obese and aged individuals. Because hepatic steatosis is closely associated with metabolic syndromes, including insulin resistance, dyslipidemia, and inflammation, numerous efforts have been made to develop compounds that ameliorate it. Here, a novel perox...

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Detalles Bibliográficos
Autores principales: Kim, Seong Min, Lee, Bonggi, An, Hye Jin, Kim, Dae Hyun, Park, Kyung Chul, Noh, Sang-Gyun, Chung, Ki Wung, Lee, Eun Kyeong, Kim, Kyung Mok, Kim, Do Hyun, Kim, Su Jeong, Chun, Pusoon, Lee, Ho Jeong, Moon, Hyung Ryong, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542266/
https://www.ncbi.nlm.nih.gov/pubmed/28545035
http://dx.doi.org/10.18632/oncotarget.17695