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Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging
Hepatic steatosis is frequently observed in obese and aged individuals. Because hepatic steatosis is closely associated with metabolic syndromes, including insulin resistance, dyslipidemia, and inflammation, numerous efforts have been made to develop compounds that ameliorate it. Here, a novel perox...
Autores principales: | Kim, Seong Min, Lee, Bonggi, An, Hye Jin, Kim, Dae Hyun, Park, Kyung Chul, Noh, Sang-Gyun, Chung, Ki Wung, Lee, Eun Kyeong, Kim, Kyung Mok, Kim, Do Hyun, Kim, Su Jeong, Chun, Pusoon, Lee, Ho Jeong, Moon, Hyung Ryong, Chung, Hae Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542266/ https://www.ncbi.nlm.nih.gov/pubmed/28545035 http://dx.doi.org/10.18632/oncotarget.17695 |
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