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Association of RASgrf1 methylation with epileptic seizures

DNA methylation, one of the mechanisms of epigenetic regulation, has been suggested to be related with epilepsy. RASgrf1 is a paternally imprinted gene and has a differentially methylated region (DMR) at the promoter that can silence gene expression. We have previously observed the down-regulation o...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoni, Peng, Xi, Wang, Liang, Fu, Xinwei, Zhou, Ji Xiu, Zhu, Binglin, Luo, Jing, Wang, Xuefeng, Xiao, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542267/
https://www.ncbi.nlm.nih.gov/pubmed/28611277
http://dx.doi.org/10.18632/oncotarget.18000