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PARP1 expression and its correlation with survival is tumour molecular subtype dependent in glioblastoma

Overexpression of PARP1 exists in various cancers, including glioblastoma (GBM). Although PARP1 inhibition is a promising therapeutic target, no comprehensive study has addressed PARP1's expression characteristics and prognostic role regarding molecular heterogeneity in astrocytomas including G...

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Detalles Bibliográficos
Autores principales: Murnyák, Balázs, Kouhsari, Mahan C., Hershkovitch, Rotem, Kálmán, Bernadette, Marko-Varga, György, Klekner, Álmos, Hortobágyi, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542272/
https://www.ncbi.nlm.nih.gov/pubmed/28654422
http://dx.doi.org/10.18632/oncotarget.18013