Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells

One of the remarkable features of cancer cells is aerobic glycolysis, a phenomenon known as the “Warburg Effect”, in which cells rely preferentially on glycolysis instead of oxidative phosphorylation (OXPHOS) as the main energy source even in the presence of high oxygen tension. Cells with dysfuncti...

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Detalles Bibliográficos
Autores principales: Li, Xiaoli, Han, Gaoyang, Li, Xiaoran, Kan, Quancheng, Fan, Zhirui, Li, Yaqing, Ji, Yasai, Zhao, Jing, Zhang, Mingzhi, Grigalavicius, Mantas, Berge, Viktor, Goscinski, Mariusz Adam, M. Nesland, Jahn, Suo, Zhenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542273/
https://www.ncbi.nlm.nih.gov/pubmed/28624784
http://dx.doi.org/10.18632/oncotarget.18199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542273/
https://www.ncbi.nlm.nih.gov/pubmed/28624784
http://dx.doi.org/10.18632/oncotarget.18199

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