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Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality

Left-right asymmetric organ development is critical to establish a proper body plan of vertebrates. In zebrafish, the Kupffer’s vesicle (KV) is a fluid-filled sac which controls asymmetric organ development, and a properly inflated KV lumen by means of fluid influx is a prerequisite for the asymmetr...

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Detalles Bibliográficos
Autores principales: Kim, Jeong-gyun, Bae, Sung-Jin, Lee, Hye Shin, Park, Ji-Hyeon, Kim, Kyu-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542556/
https://www.ncbi.nlm.nih.gov/pubmed/28771527
http://dx.doi.org/10.1371/journal.pone.0182047