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Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss

TNF-α plays a key role in the development of rheumatoid arthritis (RA) and inflammatory bone loss. Unfortunately, treatment of RA with anti-inflammatory glucocorticoids (GCs) also causes bone loss resulting in osteoporosis. Our previous studies showed that overexpression of glucocorticoid-induced le...

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Detalles Bibliográficos
Autores principales: Yang, Nianlan, Baban, Babak, Isales, Carlos M., Shi, Xing-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542557/
https://www.ncbi.nlm.nih.gov/pubmed/28771604
http://dx.doi.org/10.1371/journal.pone.0181133