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Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet

High fat diet-induced obesity is associated with inflammatory and oxidative signaling in macrophages that likely participates in metabolic and physiologic impairment. One key factor that could drive pathologic changes in macrophages is the pro-inflammatory, pro-oxidant enzyme NADPH oxidase. However,...

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Detalles Bibliográficos
Autores principales: Pepping, Jennifer K., Vandanmagsar, Bolormaa, Fernandez-Kim, Sun-Ok, Zhang, Jingying, Mynatt, Randall L., Bruce-Keller, Annadora J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542654/
https://www.ncbi.nlm.nih.gov/pubmed/28771483
http://dx.doi.org/10.1371/journal.pone.0181500