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Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice

BACKGROUND: Scrub typhus is a life-threatening disease, due to infection with O. tsutsugamushi, a Gram-negative bacterium that preferentially replicates in endothelial cells and professional phagocytes. Meningoencephalitis has been reported in scrub typhus patients and experimentally-infected animal...

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Detalles Bibliográficos
Autores principales: Soong, Lynn, Shelite, Thomas R., Xing, Yan, Kodakandla, Harica, Liang, Yuejin, Trent, Brandon J., Horton, Paulina, Smith, Kathryn C., Zhao, Zhenyang, Sun, Jiaren, Bouyer, Donald H., Cai, Jiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542690/
https://www.ncbi.nlm.nih.gov/pubmed/28742087
http://dx.doi.org/10.1371/journal.pntd.0005765