Cargando…
Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice
BACKGROUND: Scrub typhus is a life-threatening disease, due to infection with O. tsutsugamushi, a Gram-negative bacterium that preferentially replicates in endothelial cells and professional phagocytes. Meningoencephalitis has been reported in scrub typhus patients and experimentally-infected animal...
Autores principales: | Soong, Lynn, Shelite, Thomas R., Xing, Yan, Kodakandla, Harica, Liang, Yuejin, Trent, Brandon J., Horton, Paulina, Smith, Kathryn C., Zhao, Zhenyang, Sun, Jiaren, Bouyer, Donald H., Cai, Jiyang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542690/ https://www.ncbi.nlm.nih.gov/pubmed/28742087 http://dx.doi.org/10.1371/journal.pntd.0005765 |
Ejemplares similares
-
IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice
por: Shelite, Thomas R., et al.
Publicado: (2016) -
Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection
por: Trent, Brandon, et al.
Publicado: (2020) -
Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses
por: Fisher, James, et al.
Publicado: (2021) -
Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice
por: Soong, Lynn, et al.
Publicado: (2014) -
Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice
por: Liang, Yuejin, et al.
Publicado: (2022)