Fingolimod and Teriflunomide Attenuate Neurodegeneration in Mouse Models of Neuronal Ceroid Lipofuscinosis

CLN diseases are rare lysosomal storage diseases characterized by progressive axonal degeneration and neuron loss in the CNS, manifesting in disability, blindness, and premature death. We have previously demonstrated that, in animal models of infantile and juvenile forms of CLN disease (CLN1 and CLN...

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Detalles Bibliográficos
Autores principales: Groh, Janos, Berve, Kristina, Martini, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542710/
https://www.ncbi.nlm.nih.gov/pubmed/28506594
http://dx.doi.org/10.1016/j.ymthe.2017.04.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542710/
https://www.ncbi.nlm.nih.gov/pubmed/28506594
http://dx.doi.org/10.1016/j.ymthe.2017.04.021

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