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Local microRNA‐133a downregulation is associated with hypertrophy in the dyssynchronous heart

AIMS: Left bundle branch block (LBBB) creates considerable regional differences in mechanical load within the left ventricle (LV). We investigated expression of selected microRNAs (miRs) in relation to regional hypertrophy and fibrosis in LBBB hearts and their reversibility upon cardiac resynchroniz...

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Detalles Bibliográficos
Autores principales: van Middendorp, Lars B., Kuiper, Marion, Munts, Chantal, Wouters, Philippe, Maessen, Jos G., van Nieuwenhoven, Frans A., Prinzen, Frits W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542733/
https://www.ncbi.nlm.nih.gov/pubmed/28772031
http://dx.doi.org/10.1002/ehf2.12154