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TLR4 Inactivation in Myeloid Cells Accelerates Bone Healing of a Calvarial Defect Model in Mice

BACKGROUND: Toll-like receptor 4 (TLR4) has been implicated in inflammation-induced bone destruction in various chronic bone diseases; however, its direct influence on bone healing is not well understood. The authors’ previous study showed accelerated bone healing with higher osteoclastogenesis gene...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Gilbert, James R., Taylor, Gwen M., Sodhi, Chhinder P., Hackam, David J., Losee, Joseph E., Billiar, Timothy R., Cooper, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542792/
https://www.ncbi.nlm.nih.gov/pubmed/28746278
http://dx.doi.org/10.1097/PRS.0000000000003541