Cargando…

Renal Protection Mediated by Hypoxia Inducible Factor-1α Depends on Proangiogenesis Function of miR-21 by Targeting Thrombospondin 1

BACKGROUND: Angiogenesis contributes to the repair process after renal ischemia/reperfusion (I/R) injury. In the present study, we tested the role of miR-21 in the angiogenesis induced by hypoxia inducible factor (HIF)-1α through inhibiting a predicted target gene thrombospondin 1 (TSP-1). METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Xialian, Song, Nana, Zhang, Xue, Jiao, Xiaoyan, Hu, Jiachang, Liang, Mingyu, Teng, Jie, Ding, Xiaoqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Original Basic Science—General
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542793/ https://www.ncbi.nlm.nih.gov/pubmed/28737660 http://dx.doi.org/10.1097/TP.0000000000001501

Ejemplares similares

LncRNA GAS5 promotes apoptosis as a competing endogenous RNA for miR-21 via thrombospondin 1 in ischemic AKI
por: Geng, Xuemei, et al.
Publicado: (2020)

Role of miR-21 on vascular endothelial cells in the protective effect of renal delayed ischemic preconditioning
por: Xu, Xialian, et al.
Publicado: (2017)

miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation
por: Song, Nana, et al.
Publicado: (2018)

Proangiogenesis effects of compound danshen dripping pills in zebrafish
por: Hu, Yang-Xi, et al.
Publicado: (2022)

Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21
por: Xu, Xialian, et al.
Publicado: (2012)

In vivo expression of thrombospondin-1 suppresses the formation of peritoneal adhesion in rats
por: Tai, Yun-Sheng, et al.
Publicado: (2019)

CD47 Activation by Thrombospondin-1 in Lymphatic Endothelial Cells Suppresses Lymphangiogenesis and Promotes Atherosclerosis
por: Singla, Bhupesh, et al.
Publicado: (2023)

Thrombospondin-1 mimetics are promising novel therapeutics for MYC-associated medulloblastoma
por: Chan, Tiffany S Y, et al.
Publicado: (2021)

TGF-β promotes microtube formation in glioblastoma through thrombospondin 1
por: Joseph, Justin V, et al.
Publicado: (2021)

Emodin Inhibits the Indoxyl Sulfate-Induced trans-Differentiation of Vascular Smooth Muscle Cells through Upregulating Thrombospondin-1
por: Zhang, Weidong, et al.
Publicado: (2023)

Decreased Human Leukocyte Antigen-G Expression by miR-133a Contributes to Impairment of Proinvasion and Proangiogenesis Functions of Decidual NK Cells
por: Guo, Wenwei, et al.
Publicado: (2017)

Hyperuricemia increases the risk of acute kidney injury: a systematic review and meta-analysis
por: Xu, Xialian, et al.
Publicado: (2017)

Lysyl oxidase and hypoxia-inducible factor 1α: biomarkers of gastric cancer
por: Han, Ya-Lin, et al.
Publicado: (2019)

Hypoxia Inhibits Subretinal Inflammation Resolution Thrombospondin-1 Dependently
por: Touhami, Sara, et al.
Publicado: (2022)

A novel scoring system for assessing the severity of electrolyte and acid-base disorders and predicting outcomes in hospitalized patients
por: Wang, Yimei, et al.
Publicado: (2019)

Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis
por: Lorenzen, Johan M., et al.
Publicado: (2015)

The Inhibitory Effect of Lysophosphatidylcholine on Proangiogenesis of Human CD34(+) Cells Derived Endothelial Progenitor Cells
por: Zhao, Haijun, et al.
Publicado: (2021)

MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients
por: Jesionek-Kupnicka, Dorota, et al.
Publicado: (2017)

Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites
por: Feng, Shuang, et al.
Publicado: (2017)

MiR-301a transcriptionally activated by HIF-2α promotes hypoxia-induced epithelial-mesenchymal transition by targeting TP63 in pancreatic cancer
por: Zhang, Kun-Dong, et al.
Publicado: (2020)

Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
por: Ochoa, Cristhiaan D, et al.
Publicado: (2010)

Twelve-month kinetics of circulating fibrosis-linked microRNAs (miR-21, miR-29, miR-30, and miR-133a) and the relationship with extracellular matrix fibrosis in dilated cardiomyopathy
por: Rubiś, Paweł, et al.
Publicado: (2019)

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction
por: Labrousse-Arias, David, et al.
Publicado: (2016)

Decreased expression of hypoxia-inducible factor 1α (HIF-1α) in cord blood monocytes under anoxia
por: Schlegel, Christiane, et al.
Publicado: (2022)

Metabolic acidosis as a risk factor for the development of acute kidney injury and hospital mortality
por: Hu, Jiachang, et al.
Publicado: (2017)

Sirtuin1 attenuates acute liver failure by reducing reactive oxygen species via hypoxia inducible factor 1α
por: Cao, Pan, et al.
Publicado: (2022)

Hypoxia inducible factor 1α promotes interleukin-1 receptor antagonist expression during hepatic ischemia-reperfusion injury
por: Wang, Zhao-Yang, et al.
Publicado: (2022)

Protection of remote ischemic preconditioning against acute kidney injury: a systematic review and meta-analysis
por: Hu, Jiachang, et al.
Publicado: (2016)

Salvianolic Acid B Prevents Iodinated Contrast Media-Induced Acute Renal Injury in Rats via the PI3K/Akt/Nrf2 Pathway
por: Tongqiang, Liu, et al.
Publicado: (2016)

Xenon Protects Against Septic Acute Kidney Injury via miR-21 Target Signaling Pathway*
por: Jia, Ping, et al.
Publicado: (2015)

miR-21 regulates vascular smooth muscle cell function in arteriosclerosis obliterans of lower extremities through AKT and ERK1/2 pathways
por: Huang, Shuichuan, et al.
Publicado: (2018)

Corrigendum to: HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction
Publicado: (2017)

A Network Pharmacology Approach to Predict the Proangiogenesis Mechanism of Huangqi-Honghua Herb Pair after Cerebral Ischemia
por: Cao, Jinyi, et al.
Publicado: (2021)

Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway
por: Mao, Cheng-Yu, et al.
Publicado: (2022)

Hypoxia-inducible factor-1α–mediated upregulation of CD99 promotes the proliferation of placental mesenchymal stem cells by regulating ERK1/2
por: Feng, Xu-Dong, et al.
Publicado: (2021)

Role of thrombospondin-1 and thrombospondin-2 in cardiovascular diseases (Review)
por: Zhang, Kaijie, et al.
Publicado: (2020)

Effect of Hypoxia on the Differentiation and the Self-Renewal of Metanephrogenic Mesenchymal Stem Cells
por: Liu, Shaopeng, et al.
Publicado: (2017)

Actin‐like protein 8 promotes cell proliferation, colony‐formation, proangiogenesis, migration and invasion in lung adenocarcinoma cells
por: Ma, Shanwu, et al.
Publicado: (2020)

Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response
por: Stirling, Elizabeth R, et al.
Publicado: (2022)

miR-21 modulates paclitaxel sensitivity and hypoxia-inducible factor-1α expression in human ovarian cancer cells
por: XIE, ZHONGBIN, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7fln5qb5jkr381msal3ubrbf6p