Kmt5a Controls Hepatic Metabolic Pathways by Facilitating RNA Pol II Release from Promoter-Proximal Regions

H4K20 monomethylation maintains genome integrity by regulating proper mitotic condensation, DNA damage response, and replication licensing. Here, we show that, in non-dividing hepatic cells, H4K20Me1 is specifically enriched in active gene bodies and dynamically regulated by the antagonistic action...

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Detalles Bibliográficos
Autores principales: Nikolaou, Kostas C., Moulos, Panagiotis, Harokopos, Vangelis, Chalepakis, George, Talianidis, Iannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542855/
https://www.ncbi.nlm.nih.gov/pubmed/28746875
http://dx.doi.org/10.1016/j.celrep.2017.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542855/
https://www.ncbi.nlm.nih.gov/pubmed/28746875
http://dx.doi.org/10.1016/j.celrep.2017.07.003

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