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Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles

Porphyromonas gingivalis is one of the bacterial species most closely associated with periodontitis and can shed large numbers of outer membrane vesicles (OMVs), which are increasingly thought to play a significant role in bacterial virulence and pathogenicity. Macrophages are amongst the first immu...

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Detalles Bibliográficos
Autores principales: Fleetwood, Andrew J., Lee, Man K.S., Singleton, William, Achuthan, Adrian, Lee, Ming-Chin, O'Brien-Simpson, Neil M., Cook, Andrew D., Murphy, Andrew J., Dashper, Stuart G., Reynolds, Eric C., Hamilton, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543041/
https://www.ncbi.nlm.nih.gov/pubmed/28824884
http://dx.doi.org/10.3389/fcimb.2017.00351