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Tumor Necrosis Factor (TNF) Bioactivity at the Site of an Acute Cell-Mediated Immune Response Is Preserved in Rheumatoid Arthritis Patients Responding to Anti-TNF Therapy

The impact of anti-tumor necrosis factor (TNF) therapies on inducible TNF-dependent activity in humans has never been evaluated in vivo. We aimed to test the hypothesis that patients responding to anti-TNF treatments exhibit attenuated TNF-dependent immune responses at the site of an immune challeng...

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Detalles Bibliográficos
Autores principales: Byng-Maddick, Rachel, Turner, Carolin T., Pollara, Gabriele, Ellis, Matthew, Guppy, Naomi J., Bell, Lucy C. K., Ehrenstein, Michael R., Noursadeghi, Mahdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543043/
https://www.ncbi.nlm.nih.gov/pubmed/28824652
http://dx.doi.org/10.3389/fimmu.2017.00932