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Tumor Necrosis Factor (TNF) Bioactivity at the Site of an Acute Cell-Mediated Immune Response Is Preserved in Rheumatoid Arthritis Patients Responding to Anti-TNF Therapy
The impact of anti-tumor necrosis factor (TNF) therapies on inducible TNF-dependent activity in humans has never been evaluated in vivo. We aimed to test the hypothesis that patients responding to anti-TNF treatments exhibit attenuated TNF-dependent immune responses at the site of an immune challeng...
Autores principales: | Byng-Maddick, Rachel, Turner, Carolin T., Pollara, Gabriele, Ellis, Matthew, Guppy, Naomi J., Bell, Lucy C. K., Ehrenstein, Michael R., Noursadeghi, Mahdad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543043/ https://www.ncbi.nlm.nih.gov/pubmed/28824652 http://dx.doi.org/10.3389/fimmu.2017.00932 |
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