Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression

Hypoxia-inducible factors (HIFs) play a central role in the transcriptional response to changes in oxygen availability. Stability of HIFs is regulated by multi-step reactions including recognition by the von Hippel-Lindau tumour suppressor protein (pVHL) in association with an E3 ligase complex. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Wendi, Kato, Hiroyuki, Kitajima, Shojiro, Lee, Kian Leong, Gradin, Katarina, Okamoto, Takashi, Poellinger, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543055/
https://www.ncbi.nlm.nih.gov/pubmed/28775317
http://dx.doi.org/10.1038/s41598-017-05685-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543055/
https://www.ncbi.nlm.nih.gov/pubmed/28775317
http://dx.doi.org/10.1038/s41598-017-05685-3

Ejemplares similares