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Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression

Hypoxia-inducible factors (HIFs) play a central role in the transcriptional response to changes in oxygen availability. Stability of HIFs is regulated by multi-step reactions including recognition by the von Hippel-Lindau tumour suppressor protein (pVHL) in association with an E3 ligase complex. Her...

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Detalles Bibliográficos
Autores principales:	Sun, Wendi, Kato, Hiroyuki, Kitajima, Shojiro, Lee, Kian Leong, Gradin, Katarina, Okamoto, Takashi, Poellinger, Lorenz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543055/ https://www.ncbi.nlm.nih.gov/pubmed/28775317 http://dx.doi.org/10.1038/s41598-017-05685-3

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