Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

Cancer is a disease of subverted regulatory pathways. In this paper, we reconstruct the regulatory network around E2F, a family of transcription factors whose deregulation has been associated to cancer progression, chemoresistance, invasiveness, and metastasis. We integrate gene expression profiles...

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Detalles Bibliográficos
Autores principales: Khan, Faiz M., Marquardt, Stephan, Gupta, Shailendra K., Knoll, Susanne, Schmitz, Ulf, Spitschak, Alf, Engelmann, David, Vera, Julio, Wolkenhauer, Olaf, Pützer, Brigitte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543083/
https://www.ncbi.nlm.nih.gov/pubmed/28775339
http://dx.doi.org/10.1038/s41467-017-00268-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543083/
https://www.ncbi.nlm.nih.gov/pubmed/28775339
http://dx.doi.org/10.1038/s41467-017-00268-2

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