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Enriching Traditional Protein-protein Interaction Networks with Alternative Conformations of Proteins

Traditional Protein-Protein Interaction (PPI) networks, which use a node and edge representation, lack some valuable information about the mechanistic details of biological processes. Mapping protein structures to these PPI networks not only provides structural details of each interaction but also h...

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Detalles Bibliográficos
Autores principales: Halakou, Farideh, Kilic, Emel Sen, Cukuroglu, Engin, Keskin, Ozlem, Gursoy, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543104/
https://www.ncbi.nlm.nih.gov/pubmed/28775330
http://dx.doi.org/10.1038/s41598-017-07351-0